ALLOPURINOL ORAL (ZYLOPRIM) HOW MEDICINE IS ADMINISTERED? TOP Use this medicine exactly as directed on the label, unless instructed differently by your doctor * Take with food or milk to minimize stomach upset. * Drink several glasses of WATER during the day, unless otherwise directed by your doctor. WARNINGS/PRECAUTIONS: TOP * Safety of use during pregnancy has not been established. This medicine SHOULD NOT BE USED DURING PREGNANCY unless benefit justifies potential risk to the fetus. CALL YOUR DOCTOR. * This medicine may cause drowsiness, dizziness, or blurred vision. DO NOT drive or operate machines until you know how you react to this medicine. * Stop taking this medication with first sign of rash, painful urination, blood in urine, irritation of the eyes, swelling of the lips or mouth. * DO NOT DRINK alcoholic beverages or take alcohol-containing preparations while being treated with this medicine. * It may take few weeks for this medication to show complete effect. Do not discontinue unless advised by your doctor. * It is important that you do not stop taking your medications without consulting your doctor. Stop taking this medicine and notify your doctor AS SOON AS POSSIBLE if you experience: Skin rash; Joint pain; Fever. Other Common Side Effects: TOP Severe skin reactions; Chills; Sleepiness; Yellowing of eyes or skin; Stomach discomfort or pain; Diarrhea; Baldness; Liver inflammation; Abnormal blood cell count; Skin inflammation; Nose bleeding; Headache; Itching; Liver problems; A small hemorrhage; Burning pain, tingling, or numbness; Change in taste; Severe skin itching with patches; Numbness or tingling in hands and feet; Changes in urination frequency or amount; Indigestion; Nausea; Vomiting. Other Common Side Effects: If symptoms are mild but do not go away or are bothersome, check with your doctor. IF ANY OF THE ABOVE SIDE EFFECTS IS SEVERE, CALL YOUR DOCTOR IMMEDIATELY. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. This leaflet has been developed by CliniDATA Source, Inc. based primarily on labeling information provided by the manufacturer. The information does not cover all possible uses, actions, precautions, side effects, or interactions of this medicine. It is not intended as medical advice for individual patients. Copyright © CliniDATA Source, Inc. 03/14. All rights reserved